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About: Ground glass hepatocyte     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : dbo:AnatomicalStructure, within Data Space : dbpedia.org associated with source document(s)

Type: anatomical structure New Facet based on Instances of this Class

In liver pathology, a ground glass hepatocyte, abbreviated GGH, is a liver parenchymal cell with a flat hazy and uniformly dull appearing cytoplasm on light microscopy. The cytoplasm's granular homogeneous eosinophilic staining is caused by the presence of HBsAg. The appearance is classically associated with abundant hepatitis B antigen in the endoplasmic reticulum, but may also be drug-induced. In the context of hepatitis B, GGHs are only seen in chronic infections, i.e. they are not seen in acute hepatitis B. GGHs were first described by Hadziyannis et al.