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About: GLIC     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatProteinFamilies, within Data Space : dbpedia.org associated with source document(s)

Type: yago:Abstraction100002137yago:Family108078020yago:Group100031264yago:Organization108008335yago:YagoLegalActoryago:YagoLegalActorGeoyago:YagoPermanentlyLocatedEntitytelevision stationyago:SocialGroup107950920yago:Unit108189659yago:WikicatProteinFamilies New Facet based on Instances of this Class

The GLIC receptor is a bacterial (Gloeobacter) Ligand-gated Ion Channel, homolog to the nicotinic acetylcholine receptors. It is a proton-gated (the channel opens when it binds a proton, H+ ion), cation-selective channel (it selectively lets the positive ions through). Like the nicotinic acetylcholine receptors is a functional pentameric oligomer (the channel normally works as an assembly of five subunits). However while its eukaryotic homologues are hetero-oligomeric (assembled from different subunits), all until now known bacteria known to express LICs encode a single monomeric unit, indicating the GLIC to be functionally homo-oligomeric (assembled from identical subunits).