Extrafusal muscle fibers are the standard skeletal muscle fibers that are innervated by alpha motor neurons and generate tension by contracting, thereby allowing for skeletal movement. They make up the large mass of skeletal striated muscle tissue and are attached to bone by fibrous tissue extensions (tendons). Extrafusal muscle fibers are not to be confused with intrafusal muscle fibers, which are innervated by sensory nerve endings in central noncontractile parts and by gamma motor neurons in contractile ends and thus serve as a sensory proprioceptor.
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| - Extrafusal muscle fiber (en)
- Fibra muscular extrafusal (pt)
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| - Extrafusal muscle fibers are the standard skeletal muscle fibers that are innervated by alpha motor neurons and generate tension by contracting, thereby allowing for skeletal movement. They make up the large mass of skeletal striated muscle tissue and are attached to bone by fibrous tissue extensions (tendons). Extrafusal muscle fibers are not to be confused with intrafusal muscle fibers, which are innervated by sensory nerve endings in central noncontractile parts and by gamma motor neurons in contractile ends and thus serve as a sensory proprioceptor. (en)
- As fibras musculares extrafusais são as fibras musculares padrão esqueléticas, que são inervadas pelos neurônios motores alfa, e geram tensão por contração, permitindo assim o movimento do esqueleto. Eles compõem a grande massa de tecido muscular esquelético e são ligados ao osso por extensões de tecido fibroso (tendões). Fibras musculares extrafusais podem ser geradas in vitro (em um prato) a partir de células-tronco pluripotentes através de diferenciação direcionada. Isso permite estudar sua formação e fisiologia. (pt)
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| - Extrafusal muscle fiber (en)
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| - Extrafusal muscle fiber (en)
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| - Extrafusal muscle fibers are the standard skeletal muscle fibers that are innervated by alpha motor neurons and generate tension by contracting, thereby allowing for skeletal movement. They make up the large mass of skeletal striated muscle tissue and are attached to bone by fibrous tissue extensions (tendons). Each alpha motor neuron and the extrafusal muscle fibers innervated by it make up a motor unit. The connection between the alpha motor neuron and the extrafusal muscle fiber is a neuromuscular junction, where the neuron's signal, the action potential, is transduced to the muscle fiber by the neurotransmitter acetylcholine. Extrafusal muscle fibers are not to be confused with intrafusal muscle fibers, which are innervated by sensory nerve endings in central noncontractile parts and by gamma motor neurons in contractile ends and thus serve as a sensory proprioceptor. Extrafusal muscle fibers can be generated in vitro (in a dish) from pluripotent stem cells through directed differentiation. This allows study of their formation and physiology. (en)
- As fibras musculares extrafusais são as fibras musculares padrão esqueléticas, que são inervadas pelos neurônios motores alfa, e geram tensão por contração, permitindo assim o movimento do esqueleto. Eles compõem a grande massa de tecido muscular esquelético e são ligados ao osso por extensões de tecido fibroso (tendões). Cada neurônio motor alfa e as fibras musculares extrafusais inervadas por ele constituem uma unidade motora. A conexão entre o neurônio motor alfa e a fibra muscular extrafusal é uma junção neuromuscular, onde o sinal do neurônio, o potencial de ação, é transduzido na fibra muscular pelo neurotransmissor acetilcolina. Fibras musculares extrafusais não devem ser confundidas com fibras musculares intrafusais, que são inervadas por terminações nervosas sensoriais em partes centrais não contráteis e por neurônios motores gama em extremidades contráteis e, assim, servem como proprioceptores sensoriais. Fibras musculares extrafusais podem ser geradas in vitro (em um prato) a partir de células-tronco pluripotentes através de diferenciação direcionada. Isso permite estudar sua formação e fisiologia. (pt)
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| - myofibra extrafusalis (en)
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