Enterprise is an unincorporated community in Volusia County, in the U.S. state of Florida, and its former county seat. Situated on the northern shore of Lake Monroe, it is flanked by the cities of DeBary and Deltona. Enterprise was once the head of navigation on the St. Johns River and at various times, the county seat for three different counties: Mosquito, which was renamed as Orange; and lastly, for Volusia, which was formed from part of Orange County.