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Enoyl-CoA-(∆) isomerase (EC 5.3.3.8, also known as dodecenoyl-CoA-(∆) isomerase, 3,2-trans-enoyl-CoA isomerase, ∆3(cis),∆2(trans)-enoyl-CoA isomerase, or acetylene-allene isomerase, is an enzyme that catalyzes the conversion of cis- or trans-double bonds of coenzyme A (CoA) bound fatty acids at gamma-carbon (position 3) to trans double bonds at beta-carbon (position 2) as below: This enzyme has an important role in the metabolism of unsaturated fatty acids in beta oxidation.

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  • Énoyl-coenzyme A isomérase (fr)
  • Enoyl CoA isomerase (en)
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  • Enoyl-CoA-(∆) isomerase (EC 5.3.3.8, also known as dodecenoyl-CoA-(∆) isomerase, 3,2-trans-enoyl-CoA isomerase, ∆3(cis),∆2(trans)-enoyl-CoA isomerase, or acetylene-allene isomerase, is an enzyme that catalyzes the conversion of cis- or trans-double bonds of coenzyme A (CoA) bound fatty acids at gamma-carbon (position 3) to trans double bonds at beta-carbon (position 2) as below: This enzyme has an important role in the metabolism of unsaturated fatty acids in beta oxidation. (en)
  • La Δ3-cis-Δ2-trans-énoyl-CoA isomérase, ou dodécénoyl-CoA isomérase, est une isomérase qui catalyse la réaction : (3Z)-dodéc-3-énoyl-CoA (2E)-dodéc-2-énoyl-CoA. Cette enzyme assure la conversion d'une double liaison cis ou trans sur l'atome de carbone γ (position 3) en double-liaison trans sur l'atome de carbone β (position 2) d'un acide gras insaturé. Elle intervient dans la β-oxydation des acides gras insaturés portant une double liaison sur un atome de carbone impair. Elle agit en décalant la position de la double liaison de l'intermédiaire acyl-CoA et en convertissant la 3-cis ou trans-énoyl-CoA en 2-trans-énoyl-CoA. Dans la mesure où l'étape clé de la dégradation des acides gras ayant une double liaison sur un atome de carbone pair produit également de la 3-trans-énoyl-CoA chez les (fr)
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  • Δ3-Δ2-Enoyl-CoA isomerase (en)
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  • Δ3-Δ2-Enoyl-CoA isomerase (en)
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  • http://commons.wikimedia.org/wiki/Special:FilePath/1sg4.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Catalytic_Site_on_Enoyl-CoA_Isomerase_in_Yeast.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Enoyl-CoA_isomerase_reaction_cis-trans.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/MFE_or_Isomerase.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/Trimer_Disk_of_Enoyl-CoA_Isomerase_in_Yeast.png
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