About: Endoglycosidase H

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The enzyme endoglycosidase H (EC 3.2.1.96) is an enzyme with systematic name glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase. It is a highly specific endoglycosidase which cleaves asparagine-linked mannose rich oligosaccharides, but not highly processed complex oligosaccharides from glycoproteins. It is used for research purposes to deglycosylate glycoproteins and to monitor intracellular protein trafficking through the secretory pathway.

Attributes	Values
rdf:type	Thing Biomolecule Biomolecule Enzyme yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 enzyme protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459
rdfs:label	Endoglycosidase H (en)
rdfs:comment	The enzyme endoglycosidase H (EC 3.2.1.96) is an enzyme with systematic name glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase. It is a highly specific endoglycosidase which cleaves asparagine-linked mannose rich oligosaccharides, but not highly processed complex oligosaccharides from glycoproteins. It is used for research purposes to deglycosylate glycoproteins and to monitor intracellular protein trafficking through the secretory pathway. (en)
foaf:name	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (en)
name	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (en)
dcterms:subject	EC 3.2.1
Wikipage page ID	11380335 (xsd:integer)
Wikipage revision ID	1115686010 (xsd:integer)
Link from a Wikipage to another Wikipage	Endoglycosidase Endoplasmic reticulum List of enzymes Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase EC 3.2.1 Secretory pathway Enzyme Glycoproteins Streptomyces griseus Translation (genetics) Golgi apparatus Golgi alpha-mannosidase II dbr:Asparagine Mannose N-acetylglucosamine Molecular weight Ribosomes Oligosaccharides Posttranslational modification Protein trafficking Streptomyces plicatus Oligosaccharyl transferase
Link from a Wikipage to an external page	http://www.chem.qmul.ac.uk/iubmb/enzyme/EC3/2/1/96.html
sameAs	Endoglycosidase H Endoglycosidase H Endoglycosidase H Endoglycosidase H Endoglycosidase H
dbp:wikiPageUsesTemplate	dbt:EC_number dbt:Enzymes dbt:Infobox_enzyme dbt:Portal_bar dbt:Reflist dbt:Sugar_hydrolases
altnames	Endo-β-N-acetylglucosaminidase H, N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase, mannosyl-glycoprotein endo-beta-N-acetylglucosamidase, di-N-acetylchitobiosyl beta-N-acetylglucosaminidase, endo-beta-acetylglucosaminidase, endo-beta--N-acetylglucosaminidase, mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase, endoglycosidase S, endo-N-acetyl-beta-D-glucosaminidase, endo-N-acetyl-beta-glucosaminidase, endo-beta-N-acetylglucosaminidase D, endo-beta-N-acetylglucosaminidase F, endo-beta-N-acetylglucosaminidase H, endo-beta-N-acetylglucosaminidase L, glycopeptide-D-mannosyl-4-N-2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase, endoglycosidase H (en)
CAS number	37278 (xsd:integer)
EC number	3.200000 (xsd:double)
IUBMB EC number	3 (xsd:integer)
has abstract	The enzyme endoglycosidase H (EC 3.2.1.96) is an enzyme with systematic name glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase. It is a highly specific endoglycosidase which cleaves asparagine-linked mannose rich oligosaccharides, but not highly processed complex oligosaccharides from glycoproteins. It is used for research purposes to deglycosylate glycoproteins and to monitor intracellular protein trafficking through the secretory pathway. (en)
gold:hypernym	Enzyme
prov:wasDerivedFrom	wikipedia-en:Endoglycosidase_H?oldid=1115686010&ns=0
page length (characters) of wiki page	7238 (xsd:nonNegativeInteger)
EC number	3.2.1.96
foaf:isPrimaryTopicOf	wikipedia-en:Endoglycosidase_H
is Link from a Wikipage to another Wikipage of	Endoglycosidase Indiana vesiculovirus Penicillium oxalicum Lysin Trehalase Endo-N-acetyl-beta-D-glucosaminidase Endo-N-acetyl-beta-glucosaminidase Endo-beta-N-acetylglucosaminidase Endo-beta-N-acetylglucosaminidase D Endo-beta-N-acetylglucosaminidase F Endo-beta-N-acetylglucosaminidase H Endo-beta-N-acetylglucosaminidase L Endo-beta-acetylglucosaminidase Endo H Endoglycosidase S Mannosyl-glycoprotein 1,4-N-acetamidodeoxy-beta-D-glycohydrolase Mannosyl-glycoprotein endo-b-N-acetylglucosaminidase Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase Di-N-acetylchitobiosyl beta-N-acetylglucosaminidase Glycopeptide-D-mannosyl-4-N-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase Glycopeptide-D-mannosyl-N4-(N-acetyl-D-glucosaminyl)2-asparagine 1,4-N-acetyl-beta-glucosaminohydrolase N,N'-diacetylchitobiosyl beta-N-acetylglucosaminidase EC 3.2.1.96
is Wikipage redirect of	Endo-N-acetyl-beta-D-glucosaminidase

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