Elizabeth Brooke (1503–1560) was the wife of Thomas Wyatt, the poet, and the mother of Thomas Wyatt the younger who led Wyatt's Rebellion against Mary I. Her parents were Thomas Brooke, 8th Baron Cobham and Dorothy Heydon, the daughter of Sir Henry Heydon. She was the sister of George Brooke, 9th Baron Cobham and was considered a possible candidate for the sixth wife of Henry VIII of England.