About: Challenge–dechallenge

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Challenge–dechallenge–rechallenge (CDR) is a medical testing protocol in which a medicine or drug is administered, withdrawn, then re-administered, while being monitored for adverse effects at each stage. The protocol is used when statistical testing is inappropriate due to an idiosyncratic reaction by a specific individual, or a lack of sufficient test subjects and unit of analysis is the individual. During the dechallenge (withdrawal) phase, the medication is allowed to wash out of the system in order to determine what effect the medication is having on an individual.

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rdf:type	software yago:WikicatScienceExperiments yago:Ability105616246 yago:Abstraction100002137 yago:Act100030358 yago:Activity100407535 yago:Cognition100023271 yago:Event100029378 yago:Experiment100639556 yago:Investigation100633864 yago:Know-how105616786 yago:Method105660268 yago:PsychologicalFeature100023100 yago:Research100636921 yago:Work100575741 yago:YagoPermanentlyLocatedEntity yago:ScientificResearch100641820 yago:WikicatEvaluationMethods
rdfs:label	Challenge–dechallenge–rechallenge (en) Challenge–dechallenge–rechallenge (es)
rdfs:comment	Challenge–dechallenge–rechallenge (CDR) is a medical testing protocol in which a medicine or drug is administered, withdrawn, then re-administered, while being monitored for adverse effects at each stage. The protocol is used when statistical testing is inappropriate due to an idiosyncratic reaction by a specific individual, or a lack of sufficient test subjects and unit of analysis is the individual. During the dechallenge (withdrawal) phase, the medication is allowed to wash out of the system in order to determine what effect the medication is having on an individual. (en) Challenge-dechallenge-rechallenge (CDR) es un protocolo de prueba médica en el que se administra un medicamento o suplemento, se retira y luego se vuelve a administrar, mientras se monitorea en busca de efectos adversos en cada etapa. El protocolo se utiliza cuando las pruebas estadísticas son inapropiadas debido a una reacción idiosincrásica de un individuo específico, o la falta de suficientes sujetos de prueba y unidad de análisis es el individuo. Durante la fase de retirada, se permite que el medicamento se elimine del sistema para determinar qué efecto tiene el medicamento en un individuo. (es)
name	Challenge–dechallenge–rechallenge (en)
dcterms:subject	Design of experiments Medical tests
Wikipage page ID	16264545 (xsd:integer)
Wikipage revision ID	1069082849 (xsd:integer)
Link from a Wikipage to another Wikipage	Peter Breggin Eli Lilly and Company Protocol (natural sciences) Statistics Clinical trial Design of experiments Akathisia Fluoxetine Food and Drug Administration Randomized controlled trial Medical tests Adverse drug reaction CDR computerized assessment system Self-experimentation in medicine /wrists Single-subject design Adverse effect (medicine)
sameAs	Challenge–dechallenge–rechallenge Challenge–dechallenge–rechallenge Challenge–dechallenge–rechallenge Challenge–dechallenge–rechallenge
dbp:wikiPageUsesTemplate	dbt:Infobox_diagnostic dbt:Main dbt:Reflist dbt:Short_description
purpose	monitor adverse effects for drug/medication (en)
has abstract	Challenge–dechallenge–rechallenge (CDR) is a medical testing protocol in which a medicine or drug is administered, withdrawn, then re-administered, while being monitored for adverse effects at each stage. The protocol is used when statistical testing is inappropriate due to an idiosyncratic reaction by a specific individual, or a lack of sufficient test subjects and unit of analysis is the individual. During the dechallenge (withdrawal) phase, the medication is allowed to wash out of the system in order to determine what effect the medication is having on an individual. (en) Challenge-dechallenge-rechallenge (CDR) es un protocolo de prueba médica en el que se administra un medicamento o suplemento, se retira y luego se vuelve a administrar, mientras se monitorea en busca de efectos adversos en cada etapa. El protocolo se utiliza cuando las pruebas estadísticas son inapropiadas debido a una reacción idiosincrásica de un individuo específico, o la falta de suficientes sujetos de prueba y unidad de análisis es el individuo. Durante la fase de retirada, se permite que el medicamento se elimine del sistema para determinar qué efecto tiene el medicamento en un individuo. (es)
gold:hypernym	Protocol
prov:wasDerivedFrom	wikipedia-en:Challenge–dechallenge–rechallenge?oldid=1069082849&ns=0
page length (characters) of wiki page	6340 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Challenge–dechallenge–rechallenge
is Link from a Wikipage to another Wikipage of	Elimination diet Forensic epidemiology Isotretinoin Cat health CDR Challenge-dechallenge-rechallenge List of statistics articles Management of schizophrenia Challenge dechallenge rechallenge Rechallenge
is Wikipage redirect of	Challenge-dechallenge-rechallenge Challenge dechallenge rechallenge Rechallenge
is Wikipage disambiguates of	CDR
is foaf:primaryTopic of	wikipedia-en:Challenge–dechallenge–rechallenge

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