About: B3 domain

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The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors (≥40 species) (Pfam PF02362) combined with other domains (InterPro: IPR003340). It consists of 100-120 residues, includes seven beta strands and two alpha helices that form a DNA-binding pseudobarrel protein fold (SCOP 117343); it interacts with the major groove of DNA.

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rdf:type	Thing Biomolecule Biomolecule Protein yago:WikicatTranscriptionFactors yago:Abstraction100002137 yago:Attribute100024264 yago:Beginning107290905 yago:Cause107326557 yago:Chemical114806838 yago:Compound114818238 yago:Environment113934596 yago:Event100029378 yago:Factor107327805 yago:Happening107283608 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Origin107323922 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:PsychologicalFeature100023100 yago:Relation100031921 yago:YagoPermanentlyLocatedEntity protein yago:Situation113927383 yago:Sphere114514039 yago:State100024720 yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatProteinDomains yago:WikicatProteins
rdfs:label	B3 domain (en) Dominio B3 (es) B3 DNA結合ドメイン (ja) Domena B3 (pl) B3结构域 (zh)
rdfs:comment	The B3 DNA binding domain (DBD) is a highly conserved domain found exclusively in transcription factors (≥40 species) (Pfam PF02362) combined with other domains (InterPro: IPR003340). It consists of 100-120 residues, includes seven beta strands and two alpha helices that form a DNA-binding pseudobarrel protein fold (SCOP 117343); it interacts with the major groove of DNA. (en) El dominio de unión a ADN B3 (DBD) es un altamente conservado, encontrado de manera exclusiva entre los factores de transcripción de plantas vasculares (≥40 especies) combinadas con otros dominios. Se caracterizan por presentar 100-120 aminoácidos con una estructura secundaria que incluye siete láminas beta y dos hélices alfa, de modo que la estructura terciaria adquiere una forma de barril capaz de unirse al ADN. Este dominio interacciona con el surco mayor de la hélice de ADN. Los estudios evolutivos llevados a cabo han mostrado que los genes que codifican proteínas con dominios B3 han sufrido diversos eventos de duplicación. (es) B3 DNA結合ドメイン（B3 DNA binding domain）あるいはB3ドメイン（B3 domain）とは、DNA結合ドメインの一つである。転写因子のみに見られ、現在までに40種以上の転写因子（ Pfam PF02362 ）にて発見されている。それら全ての遺伝子において、B3ドメインは他のドメイン（AP2 DNA結合ドメインなど）と共に高度に保存されている(InterPro: IPR003340)。 B3ドメインは100-120アミノ酸残基で構成され、7つのベータストランドと2つのアルファヘリックスを含み、DNA結合性偽バレル構造をフォールディングにより形成する（SCOP 117343）。この立体構造はDNAの主溝と相互作用することで、B3ドメインがDNAと結合することを可能にする。 (ja) Domena B3 – wysoce domena , spotykana wyłącznie w obrębie czynników transkrypcyjnych u roślin wyższych, znaleziona przynajmniej u 40 gatunków. Składa się z innych domen. Liczy sobie 100–120 reszt aminoacylowych. Zawiera 7 harmonijek beta oraz dwie helisy alfa, tworzące wiążącą DNA strukturę, oddziałującą z rowkiem większym DNA. (pl) B3 DNA结合结构域（英語：B3 DNA binding domain）是一些转录因子中的高度保守的（DNA-binding domain，DBD）在超过40个物种（Pfam PF02362）中发现，与其它结构域一起（IPR003340）执行转录因子的功能。B3结构域的一级结构为100-120个氨基酸残基，二级结构为七个β折叠和两个α螺旋，三级结构为假棒状（pseudobarrel，），从DNA结构的大沟处结合DNA分子。 (zh)
name	B3 DNA binding domain (en)
foaf:depiction
dcterms:subject	Molecular genetics Gene expression Protein domains Transcription factors
Wikipage page ID	16898244 (xsd:integer)
Wikipage revision ID	1103685702 (xsd:integer)
Link from a Wikipage to another Wikipage	B-DNA Protein nuclear magnetic resonance spectroscopy Beta sheet DNA-binding domain Molecular genetics Arabidopsis thaliana Abscisic acid Alpha helix Gene expression Transcription factor Protein domains Transcription factors Tertiary structure Recognition sequence Auxin C-terminus DNA binding domain N-terminus Molecular modelling Restriction endonuclease Conservation (genetics) EcoRII
Link from a Wikipage to an external page	http://transcriptionfactor.org/ http://www.gene-regulation.com/pub/databases/transfac/cl.html http://www.rcsb.org/pdb/download/downloadFile.do%3FfileFormat=pdb&compression=NO&structureId=1WID https://web.archive.org/web/20081204232625/http:/www.transcriptionfactor.org/ https://web.archive.org/web/20160112180615/http:/datf.cbi.pku.edu.cn/browsefamily.php%3Ffamilyname=B3 https://web.archive.org/web/20191017060155/http:/planttfdb.cbi.pku.edu.cn/family.php%3Ffam=ARF https://web.archive.org/web/20191017060205/http:/planttfdb.cbi.pku.edu.cn/family.php%3Ffam=B3 http://www.pubmedcentral.nih.gov/picrender.fcgi%3Fartid=535885&blobname=plntcell_tpc.104.026112_abi3model.pdb http://www.pubmedcentral.nih.gov/picrender.fcgi%3Fartid=535885&blobname=plntcell_tpc.104.026112_arf1model.pdb http://planttfdb.cbi.pku.edu.cn/family.php%3Ffam=ARF http://planttfdb.cbi.pku.edu.cn/family.php%3Ffam=B3 http://planttfdb.cbi.pku.edu.cn https://web.archive.org/web/20180620084331/http:/planttfdb.cbi.pku.edu.cn/family.php%3Ffam=RAV
sameAs	B3 domain B3 domain B3 domain B3 domain B3 domain B3 domain B3 domain B3 domain B3 domain
dbp:wikiPageUsesTemplate	dbt:SCOP dbt:Cite_journal

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