Asrat Woldeyes (Amharic: አስራት ወልደየስ ; June 20, 1928 – May 14, 1999) was an Ethiopian surgeon, a professor of medicine at Addis Ababa University, and the founder and leader of the All-Amhara People's Organization (AAPO). He was jailed by the Derg and later by the Ethiopian People's Revolutionary Democratic Front (EPRDF). After his death, The Guardian described him as "successively Ethiopia's most distinguished surgeon, physician and university dean, most controversial political party leader and best known political prisoner".