Aspley Guise railway station serves the village of Aspley Guise in Bedfordshire, England. It is on the Bletchley – Bedford Marston Vale Line. The station is served by West Midlands Trains local services, operating under the London Northwestern Railway brand.The services operate using Class 230 diesel-electric multiple unit trains which are upcycled London Underground D78 Stock. It is one of the seven stations serving the Milton Keynes urban area, albeit the only one located outside the City of Milton Keynes and Buckinghamshire. In 2016/17, the station was the least used in Bedfordshire.