About: Anti-dsDNA antibodies     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Unit109465459, within Data Space : dbpedia.org associated with source document(s)
QRcode icon
http://dbpedia.org/describe/?url=http%3A%2F%2Fdbpedia.org%2Fresource%2FAnti-dsDNA_antibodies&graph=http%3A%2F%2Fdbpedia.org&graph=http%3A%2F%2Fdbpedia.org

Anti-double stranded DNA (Anti-dsDNA) antibodies are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories. They are highly diagnostic of systemic lupus erythematosus (SLE) and are implicated in the pathogenesis of lupus nephritis.

AttributesValues
rdf:type
rdfs:label
  • Anti-dsDNA antibodies (en)
  • Anticorpi anti-dsDNA (it)
  • 抗ds-DNA抗体 (ja)
  • 抗双链DNA抗体 (zh)
rdfs:comment
  • Anti-double stranded DNA (Anti-dsDNA) antibodies are a group of anti-nuclear antibodies (ANA) the target antigen of which is double stranded DNA. Blood tests such as enzyme-linked immunosorbent assay (ELISA) and immunofluorescence are routinely performed to detect anti-dsDNA antibodies in diagnostic laboratories. They are highly diagnostic of systemic lupus erythematosus (SLE) and are implicated in the pathogenesis of lupus nephritis. (en)
  • 抗ds-DNA抗体(こうダブルストランド-ディーエヌエーこうたい)は、2本鎖DNAに対する自己抗体。 (ja)
  • 抗双链DNA抗体(英語:Anti-dsDNA antibodies)是抗核抗体(Anti-nuclear antibody,ANA)中的一种,其靶标的抗原是双链DNA。一些血液检测如酶联免疫吸附试验(ELISA)和可在诊断实验室检出抗dsDNA抗体。抗dsDNA抗体在全身性紅斑狼瘡(SLE)有很高的诊断相关性,对狼瘡性腎炎的发病机制有重要作用。 (zh)
  • Gli anticorpi anti-dsDNA, anche chiamati anti-DNA nativo, sono autoanticorpi antinucleo diretti contro la doppia elica del DNA (dsDNA è sigla dell'inglese double stranded DNA), associati a numerose malattie autoimmuni, in particolare al lupus eritematoso sistemico, dove sono presenti in oltre il 70% dei casi. È stato dimostrato, inoltre, che l'85% dei pazienti positivi agli anticorpi anti-dsDNA, ma senza manifestazioni cliniche di lupus, svilupperà la malattia nel giro di pochi anni e che il valore plasmatico di tali anticorpi riflette l'andamento clinico della malattia. (it)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/DNA_ABS_HEP_CRITHIDIA_LIVER.jpg
dcterms:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
Faceted Search & Find service v1.17_git139 as of Feb 29 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 08.03.3330 as of Mar 19 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (378 GB total memory, 67 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software