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About: Amorpha-4,11-diene 12-monooxygenase     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Unit109465459, within Data Space : dbpedia.org associated with source document(s)

Type: ThingBiomoleculeBiomoleculeEnzymeyago:Abstraction100002137yago:Activator114723079yago:Catalyst114723628yago:Chemical114806838yago:Compound114818238yago:Enzyme114732946yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921enzymeyago:Substance100019613yago:Thing100002452yago:Unit109465459 New Facet based on Instances of this Class

Amorpha-4,11-diene 12-monooxygenase (EC 1.14.13.158, CYP71AV1) is an enzyme with systematic name amorpha-4,11-diene,NADPH:oxygen oxidoreductase (12-hydroxylating). This enzyme catalyses the following chemical reaction amorpha-4,11-diene + 3 O2 + 3 NADPH + 3 H+ + 3 NADP+ + 4 H2O (overall reaction)(1a) amorpha-4,11-diene + O2 + NADPH + H+ + NADP+ + H2O(1b) artemisinic alcohol + O2 + NADPH + H+ + NADP+ + 2 H2O(1c) artemisinic aldehyde + O2 + NADPH + H+ + NADP+ + H2O Amorpha-4,11-diene 12-monooxygenase is a heme-thiolate protein (P-450)