Frances Tiafoe was the defending champion but chose not to defend his title. Dan Evans won the title after defeating Jordan Thompson 6–4, 6–4 in the final.
Frances Tiafoe was the defending champion but chose not to defend his title. Dan Evans won the title after defeating Jordan Thompson 6–4, 6–4 in the final. (en)
Alex Bolt era il detentore del titolo ma ha scelto di non partecipare. In finale Daniel Evans ha sconfitto Jordan Thompson con il punteggio di 6-4, 6-4. (it)
Mužská dvouhra Rothesay Open Nottingham 2022 probíhala v první polovině června 2022. Do singlové soutěže nottinghamského tenisového challengeru hraného na trávě nastoupilo třicet dva hráčů. Obhájcem titulu byl Američan Frances Tiafoe, který do turnaje nezasáhl. (cs)