The 2021 Big Machine Spiked Coolers Grand Prix was an IndyCar motor race held on August 14, 2021 at the Indianapolis Motor Speedway Road Course. It was the 12th round of the 2021 IndyCar Series. This was also the first meeting at the Speedway since the death of Bob Jenkins. Indianapolis area resident and well-known motorsport broadcaster Jamie Little replaced Jenkins, sharing public address duties with Allen Bestwick. , who shares duties with Bestwick, does not work the Verizon 200 meeting.