The 2020–21 Syed Mushtaq Ali Trophy was the twelfth season of the Syed Mushtaq Ali Trophy, a Twenty20 cricket tournament played in India. It was contested by 38 teams, divided into six groups, with six teams in Group B. Assam, Bengal, Hyderabad, Jharkhand, Odisha and Tamil Nadu were placed in Group B, with all the matches taking place in Kolkata. Tamil Nadu won Group A to qualify for the knockout stage of the tournament.