The 2020–21 New Mexico Lobos men's basketball team represented the University of New Mexico during the 2020–21 NCAA Division I men's basketball season. The Lobos were led by fourth-year head coach Paul Weir and are members of the Mountain West Conference. Due to COVID-19 restrictions within the state of New Mexico, the Lobos did not play any of their home games at their normal home arena The Pit. Their "home" games were played at various different locations outside of the state of New Mexico. They finished the season 6–16, 2–15 in Mountain West play to finish in last place. As the No. 11 seed in the Mountain West tournament, they lost in the first round to Fresno State 77–85.