The 2016 South Alabama Jaguars football team represented the University of South Alabama in the 2016 NCAA Division I FBS football season. The Jaguars played their home games at Ladd–Peebles Stadium in Mobile, Alabama, and competed in the Sun Belt Conference. They were led by head coach Joey Jones, who was in his eighth year with the team. They finished the season 6–7, 2–6 in Sun Belt play to finish in a three-way tie for eighth place. They were invited to the Arizona Bowl where they lost to Air Force.