The 2016 Colorado Buffaloes football team represented the University of Colorado Boulder during the 2016 NCAA Division I FBS football season. Led by fourth-year head coach Mike MacIntyre, they played their home games on-campus at Folsom Field in Boulder and were members of the South Division of the Pac-12 Conference. They finished the season 10–4, 8–1 in Pac-12 play to win their first Pac-12 South Division Title. They represented the South Division in the 2016 Pac-12 Football Championship Game where they lost to Washington. They were invited to the Alamo Bowl where they lost to Oklahoma State. It was their first winning season since 2005.