The Copa Aerosur & del Sur 2010 was the eighth edition of the summer soccer tournament sponsored by Aerosur. It involved six teams from the core cities in Bolivia: Bolivar and The Strongest of La Paz, Cochabamba Aurora and Wilstermann, Blooming and Oriente Petrolero of Santa Cruz, and six teams from 2009 Copa Simón Bolívar. In the previous season, Bolivar won its first title after against Jorge Wilstermann. In this season, Bolivar wanted to defend the title and to be one of the teams with the most championships along with Blooming and Oriente Petrolero.