The 2010–11 Ukrainian Second League was the 20th season of 3rd level professional football in Ukraine. The competitions were divided into two groups according to geographical location in the country – A is western and northern Ukraine and B is eastern and southern Ukraine. The first game of the season was played on July 23, 2010 in Group A between Chornomorets-2 Odesa and Desna Chernihiv. The competition had a winter break and resumed April 9, 2011 with a rescheduled match in Group B that was moved forward from its originally scheduled date of April 22, 2011.