The 2005 NCAA Division II football season, part of college football in the United States organized by the National Collegiate Athletic Association at the Division II level, began on August 27, 2005, and concluded with the NCAA Division II Football Championship on December 10, 2005 at Braly Municipal Stadium in Florence, Alabama, hosted by the University of North Alabama. The Grand Valley State Lakers defeated the Northwest Missouri State Bearcats, 21–17, to win their third Division II national title. The Harlon Hill Trophy was awarded to Jimmy Terwilliger, quarterback from East Stroudsburg.