The 1995 SMU Mustangs football team represented Southern Methodist University (SMU) as a member of the Southwest Conference (SWC) during the 1995 NCAA Division I-A football season. Led by fifth-year head coach Tom Rossley, the Mustangs compiled an overall record of 1–10 with a mark of 0–7 in conference play, placing last out of eight teams in the SWC.