The 1965 AFL Championship Game was the American Football League's sixth championship game, played on December 26 at Balboa Stadium in San Diego, California. It matched the Western Division champion San Diego Chargers (9–2–3) and the Eastern Division champion Buffalo Bills (10–3–1) to decide the American Football League (AFL) champion for the 1965 season. The defending champion Bills entered the game as 6½ point underdogs; the Chargers had won the first regular season meeting on October 10 by a convincing 34–3 score, and tied the Thanksgiving rematch at twenty points each.