The 1946 Hardin–Simmons Cowboys football team was an American football team that represented Hardin–Simmons University in the Border Conference during the 1946 college football season. The 1946 season marked Hardin–Simmons' return to football after a three-year hiatus during World War II. In its third season under head coach Warren B. Woodson, the Cowboys compiled a perfect 11–0 record, outscored opponents by a total of 332 to 48, won the Border Conference championship, and defeated Denver in the 1947 Alamo Bowl.