The 1945 Oregon Webfoots football team represented the University of Oregon in the Pacific Coast Conference (PCC) during the 1945 college football season. In their fifth season under head coach Tex Oliver, the Webfoots compiled a 3–6 record, finished in fourth place in the PCC, and were outscored 124 to 116. The season marked the resumption of play after the conclusion of World War II; Oregon last fielded a team in 1942 and Oliver last coached them in 1941. Three home games were played on campus at Hayward Field in Eugene and one at Multnomah Stadium in Portland.