The 1906 Wyoming gubernatorial election was held on November 6, 1906. Incumbent Republican Governor Bryant B. Brooks ran for re-election to a second term. After winning renomination against some intraparty challengers, he faced State Senator Stephen Keister in the general election. Brooks was ultimately able to win re-election by an overwhelming margin, setting a record for the largest majority in a state gubernatorial election, which would not be exceeded until Governor Stanley Hathaway's re-election in 1970.