The first USS Pike (SS-6) was a Plunger-class submarine in the service of the United States Navy, later renamed as A-5. She was laid down on 10 December 1900 at San Francisco, California by Union Iron Works, launched on 14 January 1903, and commissioned on 28 May 1903 at the Mare Island Navy Yard with Lieutenant Arthur MacArthur III in command. A-5, given the alphanumeric hull number SS-6 on 17 July 1920, was decommissioned on 25 July 1921. Earmarked as a target vessel, she was struck from the Naval Vessel Register on 16 January 1922.