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About: dbr:Okadaic_acid     Goto   Sponge   Distinct   Permalink

An Entity of Type : umbel-rc:ChemicalSubstanceType, within Data Space : dbpedia.org associated with source document(s)

Type: Thingdul:ChemicalObjectchemical substanceChemical compoundyago:WikicatCarboxylicAcidsyago:Abstraction100002137yago:Acid114607521yago:CarboxylicAcid114739360yago:Chemical114806838yago:Compound114818238yago:Element114840755yago:Material114580897yago:Matter100020827yago:Part113809207yago:PhysicalEntity100001930yago:Quintessence114847103yago:Relation100031921chemical compoundyago:Substance100019613yago:WikicatEthersumbel-rc:ChemicalSubstanceType New Facet based on Instances of this Class

Okadaic acid, C44H68O13, is a toxin produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish. One of the primary causes of diarrhetic shellfish poisoning, okadaic acid is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells. A polyketide, polyether derivative of a C38 fatty acid, okadaic acid and other members of its family have shined light upon many biological processes both with respect to dinoflagellete polyketide synthesis as well as the role of protein phosphatases in cell growth.