The 2022 Uganda Cricket World Cup Challenge League B was the second round of matches in Group B of the 2019–2022 ICC Cricket World Cup Challenge League, a cricket tournament which formed part of the qualification pathway to the 2023 Cricket World Cup. All of the matches had List A status. The tournament took place in June 2022 in Uganda. Jersey won all five of their matches in Uganda, to close the gap on Uganda and Hong Kong at the top of the group table. Conversely, Bermuda lost all five of their matches, resulting in them being eliminated from reaching the World Cup Qualifier Play-off.