The 2017–18 High Point Panthers women's basketball team represents High Point University during the 2017–18 NCAA Division I women's basketball season. The Panthers, led by sixth-year head coach DeUnna Hendrix, play their home games at the Millis Athletic Convocation Center as members of the Big South Conference. They finished the season 17–14, 10–8 in Big South play to finish in fourth place. They advanced to the semifinals of the Big South women's tournament where they lost to Liberty.