The 1999 Cal State Northridge Matadors football team represented California State University, Northridge as a member of the Big Sky Conference during the 1999 NCAA Division I-AA football season. Led by first-year head coach , Cal State Northridge finished the season with an overall record of 5–6 and a mark of 4–4 in conference play, placing fifth in the Big Sky. The Matadors played home games at North Campus Stadium in Northridge, California.