The 1958 Denver Pioneers football team was an American football team that represented the University of Denver as a member of the Skyline Conference during the 1958 NCAA University Division football season. In its fourth season under head coach John Roning, the team compiled an overall record of 2–8 record with a mark of 2–5 against conference opponents, tied for sixth place in the Skyline, and was outscored by a total of 163 to 135.