@prefix foaf: .
@prefix wikipedia-en: .
@prefix dbr: .
wikipedia-en:Linaclotide foaf:primaryTopic dbr:Linaclotide .
@prefix owl: .
dbr:Liraglutide owl:differentFrom dbr:Linaclotide .
@prefix dbo: .
dbo:wikiPageWikiLink dbr:Linaclotide .
@prefix rdf: .
@prefix ns6: .
dbr:Linaclotide rdf:type ns6:ChemicalObject .
@prefix wikidata: .
dbr:Linaclotide rdf:type wikidata:Q8386 ,
dbo:Drug ,
owl:Thing ,
dbo:ChemicalSubstance ;
owl:differentFrom dbr:Liraglutide ;
owl:sameAs .
@prefix dbpedia-sr: .
dbr:Linaclotide owl:sameAs dbpedia-sr:Linaklotid ,
dbr:Linaclotide .
@prefix dbpedia-sh: .
dbr:Linaclotide owl:sameAs dbpedia-sh:Linaklotid ,
.
@prefix yago-res: .
dbr:Linaclotide owl:sameAs yago-res:Linaclotide .
@prefix dbpedia-fr: .
dbr:Linaclotide owl:sameAs dbpedia-fr:Linaclotide ,
,
wikidata:Q3832559 .
@prefix dbpedia-hu: .
dbr:Linaclotide owl:sameAs dbpedia-hu:Linaklotid ,
,
.
@prefix dbpedia-es: .
dbr:Linaclotide owl:sameAs dbpedia-es:Linaclotida ,
.
@prefix dbpedia-it: .
dbr:Linaclotide owl:sameAs dbpedia-it:Linaclotide ,
.
@prefix rdfs: .
dbr:Linaclotide rdfs:label "Linaclotide"@fr ,
"\u0644\u064A\u0646\u0627\u0643\u0644\u0648\u062A\u064A\u062F"@ar ,
"\u30EA\u30CA\u30AF\u30ED\u30C1\u30C9"@ja ,
"\u041B\u0438\u043D\u0430\u043A\u043B\u043E\u0442\u0438\u0434"@ru ,
"Linaclotida"@es ,
"Linaclotide"@it ,
"Linaclotide"@en .
@prefix dct: .
@prefix dbc: .
dbr:Linaclotide dct:subject dbc:Tetradecapeptides ,
dbc:Drugs_developed_by_AbbVie ,
dbc:Drugs_acting_on_the_gastrointestinal_system_and_metabolism ;
foaf:depiction ,
.
@prefix prov: .
dbr:Linaclotide prov:wasDerivedFrom .
@prefix gold: .
dbr:Linaclotide gold:hypernym dbr:Agonist ;
foaf:isPrimaryTopicOf wikipedia-en:Linaclotide ;
dbo:wikiPageWikiLink ,
dbr:Irritable_bowel_syndrome ,
dbr:Asparagine ,
dbr:Plecanatide ,
dbr:Cysteine ,
dbr:Alanine ,
dbr:Dehydration ,
dbr:Proline ,
dbr:Orthostatic_hypotension ,
dbr:Amino_acid ,
dbr:Uroguanylin ,
dbr:Astellas_Pharma ,
,
dbr:Ironwood_Pharmaceuticals ,
dbr:Forest_Laboratories ,
dbr:Tert-butyl ,
dbr:Threonine ,
dbr:Monsanto ,
dbr:Gerald_Fink ,
dbr:Agonist ,
dbr:Enterotoxin ,
dbr:Almirall ,
dbr:Glycine ,
dbr:Epithelium ,
dbr:Chemical_synthesis ,
dbr:Cyclic_guanosine_monophosphate ,
dbr:Smooth_muscle ,
dbr:Disulfide_bond ,
dbr:Glutamic_acid ,
dbr:Constipation ,
dbr:Cystic_fibrosis_transmembrane_conductance_regulator ,
dbr:FDA ,
,
dbr:Peptide ,
dbr:Astellas ,
dbr:Chronic_idiopathic_constipation ,
dbr:Allergan ,
dbr:Tyrosine ,
dbr:Sepracor ,
dbr:GI_tract ,
dbr:Disulfide ,
dbr:Trityl ,
dbr:Oral_administration ,
dbr:Guanylin ,
dbr:Intestine ,
dbc:AbbVie_brands ,
dbc:Peptides ,
dbr:Phenol ,
dbr:Guanylate_cyclase_2C ,
dbc:Drugs_acting_on_the_gastrointestinal_system_and_metabolism ,
dbr:Whitehead_Institute ,
dbr:Protecting_group ,
dbr:Direct-to-consumer_advertising ,
dbr:Cell_surface_receptor ,
dbr:Endogenous ,
dbr:Ion_channel ,
dbr:Escherichia_coli ,
dbr:Black_box_warning ,
;
dbo:description "\u6162\u6027\u4FBF\u79D8\u75C7\u306E\u6CBB\u7642\u85AC"@ja ,
"m\u00E9dicament"@fr ,
"chemick\u00E1 zl\u00FA\u010Denina"@sk ,
"compost qu\u00EDmic"@ca ,
"\u06A9\u06CC\u0656\u0645\u06CC\u0672\u06CC\u06CC \u0645\u064F\u0631\u064E\u06A9\u064E\u0628"@ks ,
"\u0B0F\u0B39\u0B3E \u0B0F\u0B15 \u0B14\u0B37\u0B27 \u0B2F\u0B3E\u0B39\u0B3E \u0B07\u0B30\u0B3F\u0B1F\u0B47\u0B2C\u0B4D\u0B32 \u0B2C\u0B3E\u0B71\u0B47\u0B32 \u0B38\u0B3F\u0B23\u0B4D\u0B21\u0B4D\u0B30\u0B4B\u0B2E \u0B38\u200C\u0B39\u0B3F\u0B24 \u0B15\u0B4B\u0B37\u0B4D\u0B20\u0B15\u0B3E\u0B20\u0B3F\u0B28\u0B4D\u0B5F \u0B0F\u0B2C\u0B02 \u0B05\u0B1C\u0B4D\u0B1E\u0B3E\u0B24 \u0B15\u0B3E\u0B30\u0B23 \u0B1C\u0B28\u0B3F\u0B24 \u0B15\u0B4D\u0B30\u0B28\u0B3F\u0B15 \u0B15\u0B4B\u0B37\u0B4D\u0B20\u0B15\u0B3E\u0B20\u0B3F\u0B28\u0B4D\u0B5F \u0B30\u0B4B\u0B17\u0B30 \u0B1A\u0B3F\u0B15\u0B3F\u0B24\u0B4D\u0B38\u0B3E \u0B15\u0B30\u0B3F\u0B2C\u0B3E \u0B2A\u0B3E\u0B07\u0B01 \u0B2C\u0B4D\u0B5F\u0B2C\u0B39\u0B43\u0B24 \u0B39\u0B41\u0B0F \u0964"@or ,
"komponim kimik"@sq ,
"Linaclotide"@ru ,
"composto qu\u00EDmico"@pt ,
"\u0645\u0631\u0643\u0628 \u0643\u064A\u0645\u064A\u0627\u0626\u064A"@ar ,
"chemical compound"@en ,
"kemisk forbindelse"@da ,
"chemische verbinding"@nl ,
"compositum chemicum"@la ,
"compus chimic"@ro ,
"konposatu kimiko"@eu ,
"\u09B0\u09BE\u09B8\u09BE\u09AF\u09BC\u09A8\u09BF\u0995 \u09AF\u09CC\u0997"@bn ,
"senyawa kimia"@in ,
"kemia kombina\u0135o"@eo ,
"chemiese verbinding"@af ,
"\u0445\u0435\u043C\u0438\u0441\u043A\u043E \u0441\u043E\u0435\u0434\u0438\u043D\u0435\u043D\u0438\u0435"@mk ,
"zwi\u0105zek chemiczny"@pl ,
"farmaco"@it ,
"\u0D30\u0D3E\u0D38\u0D38\u0D02\u200C\u0D2F\u0D41\u0D15\u0D4D\u0D24\u0D02"@ml ,
"\u0445\u0456\u043C\u0456\u0447\u043D\u0430 \u0441\u043F\u043E\u043B\u0443\u043A\u0430"@uk ,
"kjemisk sambinding"@nn ,
"composto qu\u00EDmico"@gl ,
"\u0137\u012Bmisks savienojums"@lv ,
"compuesto quimico"@an ,
"compuesto qu\u00EDmico"@es ,
"chemische Verbindung"@de ,
"kemiallinen yhdiste"@fi ,
"\u05EA\u05E8\u05DB\u05D5\u05D1\u05EA"@iw ,
"compuestu qu\u00EDmicu"@ast ,
"component quimic"@oc ,
"\u0584\u056B\u0574\u056B\u0561\u056F\u0561\u0576 \u0574\u056B\u0561\u0581\u0578\u0582\u0569\u0575\u0578\u0582\u0576"@hy ,
"kemi\u010Dna spojina; u\u010Dinkovina"@sl ,
"cheemesch Verbindung"@lb ,
"chemick\u00E1 slou\u010Denina"@cs .
@prefix dbp: .
@prefix dbt: .
dbr:Linaclotide dbp:wikiPageUsesTemplate dbt:Cn ,
dbt:Cascite ,
dbt:Short_description ,
dbt:Reflist ,
dbt:Distinguish ,
dbt:Drugbankcite ,
dbt:Keggcite ,
dbt:Nbsp ,
dbt:Infobox_drug ,
,
dbt:Laxatives ,
dbt:Use_dmy_dates ,
dbt:Use_American_English ,
dbt:Portal_bar ,
dbt:Stdinchicite ,
dbt:Chemspidercite ,
dbt:Failed_verification ,
dbt:Rp ,
dbt:Fdacite ;
dbp:legalEu "Rx-only"@en ;
dbp:legalUs "Rx-only"@en ;
dbp:dailymedid "Linaclotide"@en ;
dbp:medlineplus "a613007"@en ;
dbo:medlinePlus "a613007" ;
dbp:jmol "none"@en ;
dbp:atcSuffix "AX04"@en ;
dbp:iupharLigand 5017 ;
dbp:routesOfAdministration dbr:Oral_administration ;
dbp:tradename "Linzess"@en ;
dbp:verifiedfields "changed"@en ;
dbp:verifiedrevid 451564024 ;
dbo:alternativeName "Linzess"@en ;
dbp:width 315 ;
dbp:s 6 ;
dbp:legalUk "POM"@en ;
dbp:stdinchi 1 ;
dbp:smiles "O=C[C@@H]Cc6ccccc6"@en ;
dbp:c 59 ;
dbp:pubchem 16158208 ;
dbp:stdinchikey "KXGCNMMJRFDFNR-WDRJZQOASA-N"@en ;
dbp:o 21 ;
dbo:casNumber "851199-59-2" ;
dbp:n 15 ;
dbp:atcPrefix "A06"@en ;
dbp:casNumber 851199 ;
dbp:iupacName "L-Cysteinyl-L-cysteinyl-L-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-L-tyrosine cyclo,,-tris"@en ;
dbp:h 79 ;
dbp:chemspiderid 17314504 ;
dbo:pubchem "16158208" ;
dbp:caption "Linaclotide structure. A 2D line-angle schematic of linaclotide . The phenolic ring of terminal tyrosine is in the lower left corner. Exaggerated bond lengths emphasize 3 disulfide bonds between 6 cysteines ."@en ;
dbo:kegg "D09355" ;
dbp:kegg "D09355"@en ;
dbp:watchedfields "changed"@en ;
dbo:thumbnail ;
dbo:fdaUniiCode "N0TXR0XR5X" ;
dbp:unii "N0TXR0XR5X"@en .
dbr:Enterotoxin dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Forest_Laboratories dbo:wikiPageWikiLink dbr:Linaclotide .
dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Plecanatide dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:ATC_code_A06 dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Ironwood_Pharmaceuticals dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Almirall dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Actavis dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Prokinetic_agent dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Functional_constipation dbo:wikiPageWikiLink dbr:Linaclotide ;
dbo:medication dbr:Linaclotide .
dbr:Allergan dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Guanylate_cyclase_2C dbo:wikiPageWikiLink dbr:Linaclotide .
dbr:Linactolide dbo:wikiPageWikiLink dbr:Linaclotide ;
dbo:wikiPageRedirects dbr:Linaclotide .
dbr:Linzess dbo:wikiPageWikiLink dbr:Linaclotide ;
dbo:wikiPageRedirects dbr:Linaclotide .
dbr:ATC_code_A06AX04 dbo:wikiPageWikiLink dbr:Linaclotide ;
dbo:wikiPageRedirects dbr:Linaclotide .
dbr:ATCvet_code_QA06AX04 dbo:wikiPageWikiLink dbr:Linaclotide ;
dbo:wikiPageRedirects dbr:Linaclotide .
dbr:Constella dbo:wikiPageWikiLink dbr:Linaclotide ;
dbo:wikiPageRedirects dbr:Linaclotide .