This HTML5 document contains 68 embedded RDF statements represented using HTML+Microdata notation.

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Statements

Subject Item
dbr:C26H35NO6
dbo:wikiPageWikiLink
dbr:Lactimidomycin
dbo:wikiPageRedirects
dbr:Lactimidomycin
Subject Item
dbr:Lactimidomycin
rdf:type
wikidata:Q8386 owl:Thing dbo:Drug dbo:ChemicalSubstance n16:ChemicalObject
rdfs:label
Lactimidomycin
rdfs:comment
Lactimidomycin is a glutarimide antibiotic derived from the bacteria Streptomyces amphibiosporus. It has antifungal, antiviral and anti-cancer properties, acting as a direct inhibitor of protein translation in ribosomes. Antiviral activity is seen against a variety of RNA viruses including flaviviruses such as dengue fever, Kunjin virus and Modoc virus, as well as vesicular stomatitis virus and poliovirus. As lactimidomycin is a natural product containing an unusual unsaturated 12-membered lactone ring, it has been the subject of numerous total synthesis approaches.
foaf:depiction
n12:Lactimidomycin.svg
dcterms:subject
dbc:Lactones dbc:Glutarimides dbc:Antiviral_drugs dbc:Dengue_fever
dbo:wikiPageID
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dbo:wikiPageRevisionID
1094500981
dbo:wikiPageWikiLink
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dbp:c
26
dbp:casNumber
134869
dbp:chembl
1221911
dbp:chemspiderid
9844457
dbp:h
35
dbp:iupacName
4
dbp:molecularWeight
457.558
dbp:n
1
dbp:o
6
dbp:pubchem
11669726
dbp:smiles
N2CCCCCCCC\C=C\C1OCC=CCCC=CC=CC1C
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1
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OYOKHBHOTQDIPM-BRHOHSSQSA-N
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dbo:abstract
Lactimidomycin is a glutarimide antibiotic derived from the bacteria Streptomyces amphibiosporus. It has antifungal, antiviral and anti-cancer properties, acting as a direct inhibitor of protein translation in ribosomes. Antiviral activity is seen against a variety of RNA viruses including flaviviruses such as dengue fever, Kunjin virus and Modoc virus, as well as vesicular stomatitis virus and poliovirus. As lactimidomycin is a natural product containing an unusual unsaturated 12-membered lactone ring, it has been the subject of numerous total synthesis approaches.
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dbo:chEMBL
1221911
dbo:pubchem
11669726
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wikipedia-en:Lactimidomycin
Subject Item
wikipedia-en:Lactimidomycin
foaf:primaryTopic
dbr:Lactimidomycin