About: Seratrodast

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org:8891

Seratrodast (development name, AA-2414; marketed originally as Bronica) is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist used primarily in the treatment of asthma. It was the first TP receptor antagonist that was developed as an anti-asthmatic drug and received marketing approval in Japan in 1997. As of 2017 seratrodast was marketed as Bronica in Japan, and as Changnuo, Mai Xu Jia, Quan Kang Nuo in China.

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dbo:abstract
  • Seratrodast (development name, AA-2414; marketed originally as Bronica) is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist used primarily in the treatment of asthma. It was the first TP receptor antagonist that was developed as an anti-asthmatic drug and received marketing approval in Japan in 1997. As of 2017 seratrodast was marketed as Bronica in Japan, and as Changnuo, Mai Xu Jia, Quan Kang Nuo in China. Unlike thromboxane synthase inhibitors such as ozagrel, seratrodast does not affect thrombus formation, time to occlusion and bleeding time. Seratrodast has no effect on prothrombin time and activated partial thromboplastin time, thus ruling out any action on blood coagulation cascade. (en)
  • Seratrodast (łac. seratrodastum) – wielofunkcyjny organiczny związek chemiczny, pochodna 1,4-benzochinonu, agonista receptora tromboksanu A2 (TXA2), stosowany jako lek w astmie oskrzelowej. (pl)
dbo:alternativeName
  • . (en)
  • Bronica in Japan, Changnuo, Mai Xu Jia, Quan Kang Nuo in China and as Seradair in India. (en)
dbo:casNumber
  • 112665-43-7
dbo:fdaUniiCode
  • 4U58JM421N
dbo:kegg
  • D01123
dbo:pubchem
  • 2449
dbo:thumbnail
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  • 1009170743 (xsd:integer)
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  • R03 (en)
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  • DX06 (en)
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  • 22 (xsd:integer)
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  • 112665 (xsd:integer)
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  • 2355 (xsd:integer)
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  • 79200.0
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  • 26 (xsd:integer)
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  • 7 (xsd:integer)
dbp:kegg
  • D01123 (en)
dbp:legalStatus
  • Rx-only (en)
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  • 4 (xsd:integer)
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  • >96% (en)
dbp:pubchem
  • 2449 (xsd:integer)
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  • By mouth (en)
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  • CC1=CC (en)
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  • ZBVKEHDGYSLCCC-UHFFFAOYSA-N (en)
dbp:tradename
  • Bronica in Japan, Changnuo, Mai Xu Jia, Quan Kang Nuo in China and as Seradair in India. . (en)
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  • 4 (xsd:integer)
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  • changed (en)
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dbp:watchedfields
  • changed (en)
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rdfs:comment
  • Seratrodast (łac. seratrodastum) – wielofunkcyjny organiczny związek chemiczny, pochodna 1,4-benzochinonu, agonista receptora tromboksanu A2 (TXA2), stosowany jako lek w astmie oskrzelowej. (pl)
  • Seratrodast (development name, AA-2414; marketed originally as Bronica) is a thromboxane A2 (TXA2) receptor (TP receptor) antagonist used primarily in the treatment of asthma. It was the first TP receptor antagonist that was developed as an anti-asthmatic drug and received marketing approval in Japan in 1997. As of 2017 seratrodast was marketed as Bronica in Japan, and as Changnuo, Mai Xu Jia, Quan Kang Nuo in China. (en)
rdfs:label
  • Seratrodast (pl)
  • Seratrodast (en)
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