Mother Eleanor O'Byrne R.S.C.J. (September 12, 1896 – October 4, 1987) was a civil rights activist and the fifth president of Manhattanville College. She was best known for her efforts to reform the American educational system in order to provide equity for women and African Americans, as well as facilitating the transfer of the Manhattanville College campus from New York City to Purchase, New York. She later was president of Universidad del Sagrado Corazón.