About: Anthony Clifford Allison

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Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in Medical Science from the University of the Witwatersrand in 1947. He earned his PhD from the University of Oxford in 1950. After working at the Radcliffe Infirmary for two years, he worked as post-doctoral student to Linus Pauling in 1954. After teaching medicine for three years at Oxford, he worked at the Medical Research Council in London. In 1978 he simultaneously worked at the International Laboratory for Research on Animal Diseases (ILRAD) as its Director, and at the World Health Organization

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  • أنتوني كليفورد أليسون (بالإنجليزية: Anthony Clifford Allison)‏ هو عالم وراثة جنوب أفريقي، ولد في 21 أغسطس 1925 في إيست لندن في جنوب أفريقيا، وتوفي في 20 فبراير 2014 في بيلمونت في الولايات المتحدة. (ar)
  • Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in Medical Science from the University of the Witwatersrand in 1947. He earned his PhD from the University of Oxford in 1950. After working at the Radcliffe Infirmary for two years, he worked as post-doctoral student to Linus Pauling in 1954. After teaching medicine for three years at Oxford, he worked at the Medical Research Council in London. In 1978 he simultaneously worked at the International Laboratory for Research on Animal Diseases (ILRAD) as its Director, and at the World Health Organization's (WHO) Immunology Laboratory, both in Nairobi. He later became the Vice President for Research at Syntex Corporation (1981-1994). While a graduate student at Oxford, Allison joined a vocational Oxford University Expedition to Mount Kenya in 1949. He first noticed from blood samples he collected that there was an unusually high occurrence of sickle-cell trait in its less harmful (heterozygous) condition. He conceived the idea that it could be an advantageous adaptation to people constantly exposed to malaria. After he completed his doctoral research at Oxford in 1953, he investigated further. In 1954 he discovered, confirming his preconception, that people with sickle-cell trait are resistant to the deadly falciparum malaria. In the 1970s, Allison had worked out the enzyme, inosine monophosphate dehydrogenase, as a key molecule of the immune response in autoimmune diseases and in organ transplantation. Based on this, he tested the otherwise abandoned antibiotic, mycophenolate mofetil, as an inhibitor of the enzyme. After experimental success, with his wife, Elsie M. Eugui, he developed a safer derivative which was eventually approved as an immunosuppressive drug called CellCept. He contributed more that 400 technical papers and edited 12 books. (en)
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  • Tony Allison (en)
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  • 1925-08-21 (xsd:date)
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  • 2014-02-20 (xsd:date)
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  • 1925-08-21 (xsd:date)
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  • East London, South Africa (en)
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  • Miles and Joseph Mark (en)
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  • 2014-02-20 (xsd:date)
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  • Belmont, California, United States (en)
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  • Anthony Clifford Allison (en)
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  • Tony Allison (en)
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  • Helen Green (en)
  • Elsie M. Eugui (en)
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  • أنتوني كليفورد أليسون (بالإنجليزية: Anthony Clifford Allison)‏ هو عالم وراثة جنوب أفريقي، ولد في 21 أغسطس 1925 في إيست لندن في جنوب أفريقيا، وتوفي في 20 فبراير 2014 في بيلمونت في الولايات المتحدة. (ar)
  • Anthony Clifford Allison (21 August 1925 – 20 February 2014) was a South African geneticist and medical scientist who made pioneering studies on the genetic resistance to malaria. Clark completed his primary schooling in Kenya, completed his higher education in South Africa, and obtained a BSc in Medical Science from the University of the Witwatersrand in 1947. He earned his PhD from the University of Oxford in 1950. After working at the Radcliffe Infirmary for two years, he worked as post-doctoral student to Linus Pauling in 1954. After teaching medicine for three years at Oxford, he worked at the Medical Research Council in London. In 1978 he simultaneously worked at the International Laboratory for Research on Animal Diseases (ILRAD) as its Director, and at the World Health Organization (en)
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  • Anthony Clifford Allison (en)
  • أنتوني كليفورد أليسون (ar)
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  • Anthony Clifford Allison (en)
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