The Ambergate, Nottingham and Boston and Eastern Junction Railway was a British railway company, which hoped to connect Lancashire with the port of Boston, in Lincolnshire. It was authorised in 1846 but was unable to raise much money. It opened a standard gauge line from a junction near Nottingham to Grantham in 1853. At Nottingham it was to rely on the Midland Railway, but that company was hostile and obstructive.