The 2010 Conference USA football season was an NCAA football season played from September 2, 2010, through December 31, 2010. Conference USA consists of 12 football members separated into 2 divisions: East Carolina, Marshall, Memphis, Southern Miss, UAB, and UCF make up the eastern division, while Houston, Rice, SMU, Tulane, Tulsa, and UTEP comprise the western division. This was the 15th football season and 16th overall for Conference USA. Although C-USA was founded in 1995, it did not start football competition until 1996.