USS Germantown was a United States Navy sloop-of-war in commission for various periods between 1847 and 1860. She saw service in the Mexican–American War in 1847–1848 and during peacetime operated in the Caribbean, in the Atlantic Ocean off Africa and South America, and in East Asia. Scuttled at the outbreak of the American Civil War in 1861, she was captured and refloated by the Confederate States of America and placed in service with the Confederate States Navy as the floating battery CSS Germantown before again being scuttled in 1862.