Sharadchandra Shankar Shrikhande (19 October 1917 – 21 April 2020) was an Indian mathematician with notable achievements in combinatorial mathematics. He was notable for his breakthrough work along with R. C. Bose and E. T. Parker in their disproof of the famous conjecture made by Leonhard Euler dated 1782 that there do not exist two mutually orthogonal latin squares of order 4n + 2 for any n. Shrikhande's specialty was combinatorics, and statistical designs. Shrikhande graph is used in statistical designs.