Sami Venkatachalam Chetty (died 17 November 1958) was an Indian politician, businessman and Indian independence activist who served as a member of the Madras Legislative Council and Imperial Legislative Council of India, as well as President of the Madras Corporation. He is largely known for his surprise victory over Assembly Speaker R. K. Shanmukham Chetty in the 1934 elections to the Imperial Legislative Council.