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About: Push–pull perfusion     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:PsychologicalFeature100023100, within Data Space : dbpedia.org:8891 associated with source document(s)

Type: yago:WikicatBiochemistryMethodsyago:Ability105616246yago:Abstraction100002137yago:Cognition100023271yago:Know-how105616786yago:Method105660268yago:PsychologicalFeature100023100 New Facet based on Instances of this Class

Push–pull perfusion is an in vivo sampling method most commonly used for measuring neurotransmitters in the brain. Developed by J.H. Gaddum in 1960, this technique replaced the technique for observing neurotransmitters. The advent of concentric microdialysis probes in the 1980s resulted in push-pull sampling falling out of favor, as such probes require less monitoring, and are less invasive than the higher flow rate push-pull probes (>10 microliter/min), which could result in lesions if flow is unbalanced.