My Best Friend's Exorcism is a 2022 American supernatural comedy horror film directed by Damon Thomas from a screenplay by Jenna Lamia, based on the 2016 novel of the same name by Grady Hendrix. The film stars Elsie Fisher, Amiah Miller, Rachel Ogechi Kanu, and Cathy Ang. The film was released on Prime Video on September 30, 2022.