Manuel de Cendoya (? – 1673) was a Spanish soldier who served as governor of Spanish Florida (La Florida) from mid-1671 to mid-1673. His administration is remembered primarily for initiating construction of the Castillo de San Marcos, a masonry fortress whose building had first been ordered by Cendoya's predecessor, Governor Francisco de la Guerra y de la Vega, after the destructive raid of the English privateer Robert Searle in 1668. Work proceeded in 1671, although the first stone was not laid until 1672.