Lexie Lou (foaled February 26, 2011 in Ontario) is a Canadian Thoroughbred racehorse. In 2014, she won the Queen's Plate and two legs of the Canadian Triple Tiara on her way to winning three Sovereign Awards. She has also won three graded stakes in the United States and Canada, and finished second to American Horse of the Year California Chrome in the 2014 Hollywood Derby. In 2019, Lexie Lou was inducted into the Canadian Horse Racing Hall of Fame.