John Blakiston-Houston DL JP (11 September 1829 – 27 February 1920) was an Irish Member of Parliament. Blakiston-Houston was the son of Richard Bayly Blakiston-Houston (d. 1857), of Orangefield, County Down, and his wife Mary Isabella Houston. He was a grandson of Sir Matthew Blakiston, 2nd Baronet. He married Marian Gertrude Streatfield, of Sussex (d. 1890); the couple had twelve children.