John Wilkie was a Scottish footballer who played in the Football League for Blackburn Rovers and Middlesbrough. He began his career with Partick Thistle, and returned to the club eight years later for a second spell. He played alongside former Jags left-wing teammate John Campbell at Blackburn and Rangers, and would do so again briefly at Hibernian. Wilkie was selected for the Home Scots v Anglo-Scots international trial match in 1898 while with Blackburn, and again in 1904 while with Partick, but this did not lead to a cap for Scotland on either occasion.