John E. "Jack" Manning (December 20, 1853 – August 15, 1929) was an American Major League Baseball player. Born in Braintree, Massachusetts, United States, he broke into the National Association in 1873 at the age of 19. His career covered 12 seasons, eight teams, and three leagues. He was a primarily a right fielder who also played many games as a pitcher, and would play the infield positions on occasion as well. Manning died in Boston, Massachusetts, and was interred at New Calvary Cemetery in Boston.